Acoustics Today
Vera A. Khokhlova
- ISTINA http://istina.msu.ru/profile/va.khokhlova/
- ResearcherID A-2813-2012
- ResearchGate https://www.researchgate.net/profile/V_Khokhlova
- LinkedIn https://www.linkedin.com/pub/vera-khokhlova/15/a28/40a/ru
- 2012 – D.Sc. in Acoustics from M.V. Lomonosov Moscow State University (MSU)
- 1991 – PhD in Acoustics from M.V. Lomonosov Moscow State University
- 1979 – 1986 – MS Program (diploma with honors), Department of Acoustics, Physics Faculty of MSU
- 1996 – present – Associate Professor, Dept. of Acoustics, Physics Faculty of MSU;
- 1991 – 1996 – Research Scientist, Dept. of Acoustics, Physics Faculty of MSU;
- 1990 – 1991 – Junior Research Scientist; Dept. of Acoustics, Physics Faculty of MSU;
- 2015 - present – Elected Member of the Board of the Russian Acoustical Society (Member since 2001)
- 2013 - present – Associate Editor of the journal IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control
- 2012 - 2015 – Elected Member of the Executive Council of the Acoustical Society of America (ASA)
- 2004 - 2008, 2011 - 2014 – Elected Member of the Board of the International Society for Therapeutic Ultrasound (Member since 2001)
- 2009 - present – Member of the “Physical Ultrasound” division of the Scientific Council on Acoustics of the Russian Academy of Sciences
- 2008 - present – Fellow of the Acoustical Society of America (Member since 1993)
- 2008 - 2012 – Member of the Committee on Standards of ASA
- 2008 - present – Member of the International Organizing Committee of the International Symposium on Nonlinear Acoustics
- 2005 - present – Member of the Committee on International Research and Education of ASA
Publications
2019
- "Nonlinear Acoustics Today"15355–642019
- "Simulation of nonlinear trans-skull focusing and formation of shocks in brain using a fully populated ultrasound array with aberration correction"14631786–17982019
- "Irregular reflection of spark-generated shock pulses from a rigid surface: Mach-Zehnder interferometry measurements in air"
J. Acoust. Soc. Am.
145126-352019 - "Effect of surface roughness on nonlinear reflection of weak shock waves"
J. Acoust. Soc. Am.
1465in print2019 - "Accelerated thermal ablation of biological tissue volumes using HIFU beams with shock fronts"
Acoustical Physics
652141-1502019 - "Simulating and measuring the acoustic radiation force of a focused ultrasonic beam on elastic spheres in water"
Bulletin of the Russian Academy of Sciences: Physics
83177-812019
2018
- "Dependence of inertial cavitation induced by high intensity focused ultrasound on transducer f-number and nonlinear waveform distortion "
Journal of the Acoustical Society of America
14431160–11692018 - "Inactivation of planktonic escherichia coli by focused 1-MHz ultrasound pulses with shocks: efficacy and kinetics upon volume scale-up "
Ultrasound in Medicine and Biology
4491996–20082018 - "Field characterization and compensation of vibrational non-uniformity for a 256-element focused ultrasound phased array "
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
6591618–16302018 - "Method for designing multielement fully populated random phased arrays for ultrasound surgery applications "
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
654630–6372018 - "Wide-angle parabolic approximation for modeling high-intensity fields from strongly focused ultrasound transducers "
Acoustical Physics
643309-3192018 - "Use of pulse-echo ultrasound imaging in transcranial diagnostics of brain structures"
Bulletin of the Russian Academy of Sciences: Physics
825507–5112018 - "Mechanical decellularization of tissue volumes using boiling histotripsy"
Phys. Med. Biol.
63232350232018
2017
- "A prototype therapy system for transcutaneous application of boiling histotripsy"
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
64101542-15572017 - "Design of HIFU transducers for generating specified nonlinear ultrasound fields"
IEEE Trans. Ultrason., Ferroelect., Freq. Contr.
642374 – 3902017 - "Shock formation and nonlinear saturation effects in the ultrasound field of a diagnostic curvilinear probe"
J. Acoust. Soc. Am.
14142327-23372017 - "On the Possibility of Using Multi-Element Phased Arrays for Shock-Wave Action on Deep Brain Structures"
Acoust. Phys.
635531-5402017 - "Numerical Approaches to Simulating Nonlinear Ultrasound Fields Generated by Diagnostic-Type Transducers"
Bulletin of the Russian Academy of Sciences: Physics
818927-9312017 - "Dependence of boiling histotripsy treatment efficiency on HIFU frequency and focal pressure levels"
Ultrasound in Medicine and Biology
4391975-19852017
2016
- "Setting boundary conditions to the Khokhlov–Zabolotskaya equation for modeling ultrasound fields generated by strongly focused transducers"
Acoustical Physics
622151–1592016 - "Design of HIFU transducers to generate specific nonlinear ultrasound fields"
Physics Procedia
87132 – 1382016 - "An ultrasonic caliper device for measuring acoustic nonlinearity"
Physics Procedia
8793 – 982016
2015
- "Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications"
Int. J. Hyperthermia
312145-1622015 - "Investigation into the mechanisms of tissue atomization by high intensity focused ultrasound"
Ultrasound in Medicine & Biology
4151372-13852015 - "Acoustic holography as a metrological tool for characterizing medical ultrasound sources and fields"
J. Acoust. Soc. Am.
13831515-15322015 - "New methods and transducer designs for ultrasonic diagnostics and therapy"
Physics procedia
701152-11562015 - "Analytical Method for Evaluating the Quality of Acoustic Fields Radiated by a Multielement Therapeutic Array with Electronic Focus Steering"
Acoustical Physics, 2015
61152-592015 - "Spiral arrangement of elements of two-dimensional ultrasonic therapeutic arrays as a way of increasing the intensity at the focus"
Bulletin of the Russian Academy of Sciences. Physics
79101232–12372015 - "Ultrasonic atomization of liquids in drop-chain acoustic fountains"
J. Fluid Mech. (2015)
766129-1462015 - "Application of a Mach–Zehnder interferometer to the observation of mach stem formation when a shock wave is reflected from a rigid surface"
Bulletin of the Russian Academy of Sciences: Physics.
79101293-12952015 - "Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications"
Int J Hyperthermia, 2015
312145-1622015 - "Effect of the Angular Aperture of Medical Ultrasound Transducers on the Parameters of Nonlinear Ultrasound Field with Shocks at the Focus"
Acoustical Physics, 2015
613301-3072015 - "Characterization of spark-generated N-waves in air using an optical schlieren method"
J. Acoust. Soc. Am.
13763244-32522015 - "Investigation into the mechanisms of tissue atomization by high intensity focused ultrasound"
Ultrasound in Med. & Biol.
4151372-13852015 - "Mach-Zehnder interferometry method for acoustic shock wave measurements in air and broadband calibration of microphones"
J. Acoust. Soc. Am.
13763314-33242015 - "Mach stem formation in reflection and focusing of weak shock acoustic pulses"
J. Acoust. Soc. Am.
137EL436436–4422015 - "Application of ultrasound phased arrays with different number of elements for irradiation of tissue behind the ribs"
Memoirs of the Faculty of Physics
51453422015
2014
- "Measurement and modeling of acoustic field of a therapeutic multielement transducer in a wide range of acoustic intensities up to appearance of saturation effect in the focus"
Memoirs of the Faculty of Physics
51453462014 - "Ultrasound-guided tissue fractionation by high intensity focused ultrasound in an in vivo porcine liver model"
PNAS
111228161-81662014 - "Counterpropagation of Waves with Shock Fronts in a Nonlinear TissueLike Medium"
Acoustical Physics, 2014
604387–3972014 - "Laboratory-scale experiment to study nonlinear N-wave distortion by thermal turbulence"
J. Acoust. Soc. Am.
1362556-5662014 - "Histological analysis of mechanical lesions induced by high intensity focused ultrasound in ex-vivo human and porcine kidneys"
Memoirs of the Faculty of Physics
51453432014 - "Determination of the parameters of a high power ultrasound transducer to provide certain shock amplitude at the focus"
Memoirs of the Faculty of Physics
51453142014
2013
- "Characterization of a Multi-Element Clinical HIFU System Using Acoustic Holography and Nonlinear Modeling"
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
6081683-16982013 - "Infrared mapping of ultrasound fields generated by medical transducers: Feasibility of determining absolute intensity levels"
J. Acoust. Soc. Am.
13421586–15972013 - "Histological and biochemical analysis of mechanical and thermal bioeffects in boiling histotripsy lesions induced by high intensity focused ultrasound"
Ultrasound in Medicine & Biology
393424-4382013 - "The role of acoustic nonlinearity in tissue heating behind a rib cage using high intensity focused ultrasound phased array"
Phys. Med. Biol.
5882537-25592013 - "Introduction to the special issue on therapeutic ultrasound"
J. Acoust. Soc. Am.
134214412013 - "Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shockwave therapy device"
J. Acoust. Soc. Am.
13421663-16742013 - "Histological analysis of mechanical lesions induced by high intensity focused ultrasound in ex-vivo human and porcine kidneys"
Memoirs of the Faculty of Physics
393424-4382013
2012
- "Mechanisms for saturation of nonlinear pulsed and periodic signals in focused acoustic beams"
Acoust. Phys.
58181–892012 - "Ultrasonic atomization of tissue and its role in tissue fractionation by high intensity focused ultrasound"
Phys. Med. Biol.
57238061-80782012 - "Disintegration of tissue using high intensity focused ultrasound: Two approaches that utilize shock waves"
Acoustics Today
8424-362012
2011
- "Nonlinear acoustic N-wave random focusing in fully developed turbulence: laboratory scale experiment"
J. Acoust. Soc. Am.
13063595-36072011 - "Simulation of three dimensional nonlinear fields of ultrasound therapeutic arrays"
Acoustical Physics
573334–3432011 - "Simulation of three-dimensional nonlinear fields of ultrasound therapeutic arrays"
Acoust. Phys.
573334-3432011 - "Simulation of thermal lesions in biological tissues irradiated by high-intensity focused ultrasound through the rib cage"
Physics of Wave Phenomena
19162-672011 - "Nonlinear and diffraction effects in propagation of N-waves in randomly inhomogeneous moving media"
J. Acoust. Soc. Am.
12941760-17722011 - "Controlled tissue emulsification produced by high intensity focused ultrasound shock waves and millisecond boiling"
J. Acoust. Soc. Am.
13053498-35102011
2010
- "Statistical properties of nonlinear diffracting N-wave behind a random phase screen"
Acoust. Phys.
562158-1672010 - "Shock-induced heating and millisecond boiling in gels and tissue due to high intensity focused ultrasound"
Ultrasound in Medicine & Biology
362250-2672010 - "Focusing of high intensity ultrasound through the rib cage using a therapeutic random phased array"
Ultrasound in Medicine & Biology
366888-9062010 - "A derating method for therapeutic applications of high intensity focused ultrasound"
Acoust. Phys.
563376–3852010 - "Distortion of the field of a focused finite_amplitude ultrasonic beam behind the random phase layer"
Acoust. Phys.
564467–4742010 - "Focus splitting associated with propagation of focused ultrasound through the rib cage"
Acoust. Phys.
565665–6742010 - "Nonlinear propagation of spark-generated N-waves in air: Modeling and measurements using acoustical and optical methods"
J. Acoust. Soc. Am.
12863321-33332010 - "Feasibility of noninvasive ultrasound surgery behind the rib cage"
Medical Physics
353–642010
2009
- "Spatial structure of high intensity focused ultrasound beams of various geometry"
Physics of Wave Phenomena
17145-492009 - "Magnetic resonance imaging of boiling induced by high intensity focused ultrasound"
J. Acoust. Soc. Am.
12552420-24312009 - "Focusing of high power ultrasound beams and limiting values of shock wave parameters"
Acoust. Phys.
554-5463–4732009 - "Diffraction effects accompanying focused ultrasonic pulse propagation in a medium with a thermal inhomogeneity"
Acoust. Phys.
554-5474–4812009
2008
- "Nonlinear spherically divergent shock waves propagating in a relaxing medium"
Acoust. Phys.
54132–412008 - "Acoustic characterization of high intensity focused ultrasound fields: A combined measurement and modeling approach"
J. Acoust. Soc. Am.
12442406-24202008
2006
- "Effects of nonlinear propagation, cavitation, and boiling in lesion formation by high intensity focused ultrasound in a gel phantom"
J. Acoust. Soc. Am.
11931834 - 18482006 - "Monitoring of temperature evolution within the focal zone of ultrasound transducer"
Acoust. Phys.
522119 - 1242006 - "Nonlinear pulsed ultrasound beams radiated by rectangular focused diagnostic transducers"
Acoust. Phys.
524481–4892006 - "Parabolic equation for nonlinear acoustic wave propagation in inhomogeneous moving media"
Acoust. Phys.
526725-7352006 - "Use of a bovine eye lens for observation of HIFU-induced lesions in real-time"
Ultrasound in Med. and Biol.
32111731-17412006
2004
- "Heating of biological tissues by two-dimensional phased arrays with random and regular element distribution"
Acoust. Phys.
502222-2312004 - "Nonlinear waveform distortion and shock formation in the near field of a continuous wave piston source"
J. Acoust. Soc. Am.
1155(1)1982-19872004 - "Effect of frequency-dependent absorption on propagation of nonlinear acoustic wave with shocks"
Physics of Wave Phenomena
123126-1322004
2003
- "Physical mechanisms of the therapeutic effect of ultrasound"
Acoust. Phys.
494369-3882003
2002
- "Effect of overpressure and pulse repetition frequency on cavitation in shock wave lithotripsy"
J. Acoust. Soc. Am.
1123(1)1183 - 11952002
2001
- "Use of overpressure to assess the role of bubbles in focused ultrasound lesion shape in vitro"
Ultrasound in Med. and Biol.
275695 –7082001 - "Numerical modeling of finite amplitude sound beams: Shock formation in the nearfield of a cw plane piston source"
J. Acoust. Soc. Am.
110195-1082001 - "Effect of acoustic nonlinearity on heating of biological tissue induced by high intensity focused ultrasound"
Acoust. Phys.
474468-4752001
2000
- "Nonlinear distortion and attenuation of intense acoustic waves in lossy media obeying a frequency power law"
Acoustical Physics
462170-1772000 - "Thermal phenomena at focusing a powerful ultrasonic beam in a two-layer (water – biological tissue) medium"
Bulletin of the Russian Academy of Sciences, Physics
64121854-18582000 - "Effects of nonlinear saturation for acoustic waves propagating in a medium with frequency dependent gain"
Bulletin of the Russian Academy of Sciences, Physics
64121850-18532000 - "Numerical modeling of nonlinear waves with shocks in a waveform and waveform derivative"
Mosc. Univ. Phys. Bull. , ser. 3, Physics and Astronomy
128-312000 - "Numerical simulations of heating patterns and tissue temperature response due to high-intensity focused ultrasound"
IEEE Trans. Ultrason., Ferroelect., Freq. Contr.
4741077-10892000
1999
- "Diagnostics of a relaxing medium by an acoustic pulse with shock front."
Acoustical Physics
4518-131999 - "Nonlinear and diffraction effects in acoustic beams of cylindrical symmetry"
Acoustical Physics
455615-6211999 - "Modeling of thermal processes in biological tissue induced by focused ultrasound"
Mosc. Univ. Phys. Bull., ser. 3, Physics and Astronomy
29-311999
1998
- "Nonlinear Evolution of Single Shock Pulse in Medium with Power Frequency Law of Absorption"
Proc. of Academy of Sciences, ser. Physics
62122375-23781998
1997
- "New method of calculation of paraxial region of intense acoustic beams"
Acoustical Physics
43139-441997 - "Analytical method for describing the paraxial region of finite amplitude sound beams"
J. Acoust. Soc. Am.
10131298-13081997
1996
- "A modification of the spectral description of nonlinear acoustic waves with discontinuities"
Acoustical Physics
423362-3671996 - "Fluctuation characteristics of a sonic boom after passing through randomly inhomogeneous layer"
Acoustical Physics
425550-5541996
1994
- "Statistics of Sawtooth Acoustic Waves with Random Space Modulation"
Acoustical Physics
401111-1151994
1991
- "Kinetics of one-dimensional sawtooth waves"
Sov. Phys. Acoust
37190-931991 - "Transformation of the two-point distribution functions of the parameters of a sound field in a nonlinear medium"
Sov. Phys. Acoust
374369-3721991
1989
- "The kinetic equation of the one-dimensional acoustical turbulence"
Vestn. Mosk. Univ.3 , Fiz. Astron.(USSR)
3064-691989
1988
- "Kinetic approach to the description of one-dimensional acoustical turbulence"
Sov. Phys. Acoust. (USA)
34289-2921988
1987
- "The statistical characteristics of high intensity diffracting acoustical noise"
Mosc. Univ. Phys. Bull. (USA)
4259-631987 - "On nonlinear and diffraction effects in the sound beams with the random cross structure"
Sov. Phys. Acoust. (USA)
33195-1991987
1986
- "Calculation of the statistical characteristics of diffracting high intensity acoustical noise"
Mosc. Univ. Phys. Bull. (USA)
41537-421986
1985
- "Suppression of nonlinear damping of a sound wave in a medium which contains a resonant absorber with a finite line width"
Mosc. Univ. Phys. Bull. (USA)
4067-711985