Maria M. Karzova

Ph.D., 2016
Database information: 
Areas of Research Activity: 
General topics of nonlinear wave physics
High-intensity focused ultrasound (HIFU) in therapy and noninvasive surgery
Kidney stone fragmentation by ultrasound waves
Metrology of ultrasound sources and their fields
Nonlinear problems in aeroacoustics
Numerical modeling in acoustics
Education: 
  • 2016 – PhD in Acoustics from M.V. Lomonosov Moscow State University (MSU) and Ecole Centrale de Lyon, France (ECL)
  • 01.03.2012 – 01.04.2016 – PhD Program: cotutelle program between Department of Acoustics, Physics Faculty, Moscow State University (Russia) and Ecole Centrale de Lyon, LMFA laboratory (France). Specialization: Acoustics, thesis title: “Nonlinear focusing and reflection of shock pulses and high intensity ultrasound waves: applications in medical ultrasound and aeroacoustics”. Co-Supervisors: Dr. Vera A. Khokhlova (in Russia), Dr. Philippe Blanc-Benon (in France). PhD thesis title: "Nonlinear focusing and reflection of shock acoustic waves: applications in medical ultrasound and aeroacoustics".
  • 01.09.2010 – 31.01.2012 – MS Program (diploma with honors), Department of Acoustics, Physics Faculty, M.V. Lomonosov Moscow State University (Russia). Branch: Fundamental radiophysics and Physical electronics, speciality: Physical acoustics. Thesis title: “Saturation mechanisms of shock wave parameters in pulsed and periodic high-intensity focused ultrasound beams”.
  • 01.09.2006 – 30.06.2010 – BS Program, Department of Acoustics, Physics Faculty, M.V. Lomonosov Moscow State University (Russia).
  • 01.09.2004 – 30.06.2006 – high school, Moscow State University Advanced Educational Center (Russia).
Professional position: 
  • 2019 – present  – Senior Researcher, Dept. of General Physics and Condensed Matter Physics, Physics Faculty of MSU
  • 2016 – 2019 – Research fellow, Dept. of Acoustics, Physics Faculty, M.V. Lomonosov Moscow State University
Honors/Awards: 
  • 2022-present  Grant of the Russian Scientific Foundation "The use of shock-waves to accelerate volumetric thermal ablation of biological tissues by high-intensity focused ultrasound"
  • 2020, 2022  Rector's scholarship for young scientists from M.V. Lomonosov Moscow State University 
  • 2019-2021  Grant from Russian Foundation for Basic Research (RFBR) "New approaches to volumetric thermal ablation of biological tissues by focused ultrasound with high-amplitude shock fronts in non-invasive surgery applications"
  • 2018 Award and medal of the Russian Acoustical Society named after L.M. Brekhovskikh
  • 2017 Grant of the Russian Scientific Foundation "Effects of atmospheric turbulence and irregular reflection from rigid surfaces on the parameters of a sonic boom wave in relation to the problems of aeroacoustics"
  • 2016  Award for young scientists of Faculty of Physics of Moscow State University
  • 2016-2018  Scholarship from the President of Russia for young scientists 
  • 2015  Award for young scientists of Moscow State University
  • 2013  Grant from the International Commission for Acoustics and Acoustical Society of America for excellent contributions to Acoustics
  • 2013  Award for the best student poster presentation at the 4th Winter School on Therapeutic Ultrasound (17-22 March, Les Houches, France)
  • 2012-2013  Grant of the Russian Foundation for Basic Research for young scientists, RFBR 12-02-31830, “Experimental and numerical study of the spatial and temporal structure of acoustical fields with shocks in the processes of nonlinear focusing and reflection from boundaries” 
  • 2012-2015  Scholarship from the French Government for joint PhD Program between Moscow State University (Russia) and Ecole Centrale de Lyon (France)
  • 2012  Award for the best student presentation at the XXV Session of the Russian Acoustical Society, section on Nonlinear acoustics
  • 2012  First place at the R.V. Khokhlov contest of the best MS student thesis at the Physics Department of Moscow State University
  • 2011-2012  M.V.Lomonosov stipend for excellence in research and studies at the Physics Department of Moscow State University
  • 2011  Award from the Acoustical Society of America (Student Stipend Program) to assist the research of promising graduate students in acoustics
  • 2011  Student stipend in theoretical physics from Dynasty Foundation
  • 2011  Award for the best student presentation at the XXIV Session of the Russian Acoustical Society, section on Nonlinear acoustics
Show additional information Show publications

Publications

2023

  1. P.B. Rosnitskiy, S.A. Tsysar, M.M. Karzova, S.V. Buravkov, P.G. Malkov, N.V. Danilova, E.M. Ponomarchuk, O.A. Sapozhnikov, T.D. Khokhlova, G.R. Schade, A.D. Maxwell, Y.N. Wang, A.V. Kadrev, A.L. Chernyaev, D.A. Okhobotov, A.A. Kamalov, and V.A. Khokhlova
    "Pilot ex vivo study on non-thermal ablation of human prostate adenocarcinoma tissue using boiling histotripsy"

    Ultrasonics,

    133
    107029
    1-8, DOI: 10.1016/j.ultras.2023.107029
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  2. V.A. Khokhlova, P.B. Rosnitskiy, S.A. Tsysar, S.V. Buravkov, E.M. Ponomarchuk, O.A. Sapozhnikov, M.M. Karzova, T.D. Khokhlova, A.D. Maxwell, Y.N. Wang, A.V. Kadrev, A.L. Chernyaev, V.P. Chernikov, D.A. Okhobotov, A.A. Kamalov, and G.R. Schade
    "Initial assessment of boiling histotripsy for mechanical ablation of ex vivo human prostate tissue"

    Ultrasound in Medicine and Biology,

    49
    1
    62–71, DOI: 10.1016/j.ultrasmedbio.2022.07.014
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  3. R.P. Williams, M.M. Karzova, P.V. Yuldashev, A.Z. Kaloev, F.A. Nartov, V.A. Khokhlova, B.W. Cunitz, K.P. Morrison, and T.D. Khokhlova
    "Dual-mode 1-D linear ultrasound array for image-guided drug delivery enhancement without ultrasound contrast agents"

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control,

    70
    7
    693–707, DOI: 10.1109/tuffc.2023.3268603
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  4. M.M. Karzova, W. Kreider, A. Partanen, T.D. Khokhlova, O.A. Sapozhnikov, P.V. Yuldashev, and V.A. Khokhlova
    "Comparative characterization of nonlinear ultrasound fields generated by Sonalleve V1 and V2 MR-HIFU systems"

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control,

    70
    6
    521–537, DOI: 10.1109/TUFFC.2023.3261420
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  5. P.A. Pestova, M.M. Karzova, P.V. Yuldashev, and V.A. Khokhlova
    "The use of focused ultrasound beams with shocks to suppress diffusion effects in volumetric thermal ablation of biological tissue"

    Acoustical Physics,

    69
    4
    448–458, DOI: 10.1134/S1063771023600468
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2021

  1. P.V. Yuldashev, M.M. Karzova, W. Kreider, P.B. Rosnitskiy, O.A. Sapozhnikov and V.A.Khokhlova.
    "“HIFU beam”: a simulator for predicting axially symmetric nonlinear acoustic fields generated by focused transducers in a layered medium"

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Sept. 2021,

    68
    9
    2837–2852. DOI: 10.1109/TUFFC.2021.3074611
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  2. M.M. Karzova, P.V. Yuldashev, V.A. Khokhlova, F.A. Nartov, K.P. Morrison and T.D. Khokhlova
    "Dual-use transducer for ultrasound imaging and pulsed focused ultrasound (pFUS) therapy"

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Sept. 2021

    68
    9
    2930–2941. DOI: 10.1109/TUFFC.2021.3070528
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  3. E.M. Ponomarchuk, P.B. Rosnitskiy, T.D. Khokhlova, S.V. Buravkov, S.A. Tsysar, M.M. Karzova, K.D. Tumanova, A.V. Kunturova, Y.N. Wang, O.A. Sapozhnikov, P.E. Trakhtman, N.N. Starostin, and V.A. Khokhlova
    "Ultrastructural analysis of volumetric histotripsy bio-effects in large human hematomas"

    Ultrasound in Medicine and Biology

    47
    9
    2608–2621. DOI: 10.1016/j.ultrasmedbio.2021.05.002
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  4. P.V. Yuldashev, M.M. Karzova, V.A. Khokhlova, and Ph Blanc-Benon
    "Numerical simulation of a nonlinear parabolic equation for analyzing the perceived loudness statistics of sonic boom wave after propagation through atmospheric turbulent layer"

    Acoustical Physics

    67
    1
    26-37
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  5. P.A. Pestova, M.M. Karzova, P.V. Yuldashev, W. Kreider, and V.A. Khokhlova
    "Impact of treatment trajectory on temperature field uniformity in biological tissue irradiated by ultrasound pulses with shocks"

    Acoustical Physics

    67
    3
    250–258

2019

  1. M.M. Karzova, T. Lechat, S. Ollivier, D. Dragna, P.V. Yuldashev, V.A. Khokhlova, P. Blanc-Benon
    "Irregular reflection of spark-generated shock pulses from a rigid surface: Mach-Zehnder interferometry measurements in air"

    The Journal of the Acoustical Society of America

    145
    1
    26-35
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  2. M.M. Karzova, T. Lechat, S. Ollivier, D. Dragna, P. Yuldashev, V.A. Khokhlova, P. Blanc-Benon
    "Effect of surface roughness on nonlinear reflection of weak shock waves"

    The Journal of the Acoustical Society of America

    146
    5
    438-443
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  3. Y.S. Andriyakhina, M.M. Karzova, P.V. Yuldashev, V.A. Khokhlova
    "Accelerated thermal ablation of biological tissue volumes using HIFU beams with shock fronts"

    Acoustical Physics

    65
    2
    141-150
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  4. A.V. Nikolaeva, M.M. Karzova, S.A. Tsysar, V.A. Khokhlova, O.A. Sapozhnikov
    "Simulating and measuring the acoustic radiation force of a focused ultrasonic beam on elastic spheres in water"

    Bulletin of the Russian Academy of Sciences: Physics

    83
    1
    77-81
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  5. V.A. Khokhlova, P.B. Rosnitskiy, S.A. Tsysar, S.V. Buravkov, O.A. Sapozhnikov, M.M. Karzova, T.D. Khokhlova, A.D. Maxwell, N.M. Gaifullin, A.V. Kadrev, D.A. Okhobotov, A.A. Kamalov, G.R. Schade
    "A novel method for non-invasive mechanical ablation of prostate tumors using pulsed focused ultrasound"

    Urologiia

    6
    67-73 (in Russian)
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2017

  1. M.M. Karzova, P.V. Yuldashev, O.A. Sapozhnikov, V.A. Khokhlova, B.W. Cunitz, W. Kreider, M.R. Bailey
    "Shock formation and nonlinear saturation effects in the ultrasound field of a diagnostic curvilinear probe"

    The Journal of the Acoustical Society of America

    141
    4
    2327-2337
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  2. Terzi, M.E., Tsysar, S.A., Yuldashev, P.V., Karzova, M.M., and Sapozhnikov, O.A.
    "Generation of a vortex ultrasonic beam with a phase plate with an angular dependence of the thickness"

    Moscow University Physics Bulletin

    72
    1
    61–67
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  3. Karzova M.M., Yuldashev P.V., Rosnitskiy P.B., Khokhlova V.A.
    "Numerical Approaches to Simulating Nonlinear Ultrasound Fields Generated by Diagnostic-Type Transducers"

    Bulletin of the Russian Academy of Sciences: Physics

    81
    8
    927-931
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2015

  1. M.M. Karzova, P.V. Yuldashev, V.A. Khokhlova, S. Ollivier, E. Salze, Ph. Blanc-Benon
    "Characterization of spark-generated N-waves in air using an optical schlieren method"

    The Journal of the Acoustical Society of America

    137
    6
    3244-3252
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  2. P.V. Yuldashev, M.M. Karzova, V.A. Khokhlova, S. Ollivier, Ph. Blanc-Benon
    "Mach-Zehnder interferometry method for acoustic shock wave measurements in air and broadband calibration of microphones"

    The Journal of the Acoustical Society of America

    137
    6
    3314-3324
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  3. M.M. Karzova, V.A. Khokhlova, E. Salze, S. Ollivier, Ph. Blanc-Benon
    "Mach stem formation in reflection and focusing of weak shock acoustic pulses"

    The Journal of the Acoustical Society of America

    137
    EL436
    436–442
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  4. M. M. Karzova , P. V. Yuldashev, V. A. Khokhlova, S. Ollivier, Ph. Blanc-Benon
    "Application of a Mach–Zehnder interferometer to the observation of mach stem formation when a shock wave is reflected from a rigid surface"

    Bulletin of the Russian Academy of Sciences: Physics.

    79
    10
    1293-1295
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2013

  1. C. Perez, H. Chen, T.J. Matula, M.S. Karzova, V.A. Khokhlova
    "Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shockwave therapy device"

    J. Acoust. Soc. Am.

    134
    2
    1663-1674

2012

  1. M.M. Karzova, M.V. Averiyanov, O.A. Sapozhnikov, and V.A. Khokhlova
    "Mechanisms for saturation of nonlinear pulsed and periodic signals in focused acoustic beams"

    Acoust. Phys.

    58
    1
    81–89
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