Vera A. Khokhlova

Doctor of Science
Education: 
  • 2012 – D.Sc. in Acoustics from M.V. Lomonosov Moscow State University (MSU)
  • 1991 – PhD in Acoustics from M.V. Lomonosov Moscow State University
  • 1979 – 1986 – MS Program (diploma with honors), Department of Acoustics, Physics Faculty of MSU
Professional position: 
  • 1996 – present – Associate Professor, Dept. of Acoustics, Physics Faculty of MSU; 
  • 1991  1996 – Research Scientist, Dept. of Acoustics, Physics Faculty of MSU;
  • 1990  1991  Junior Research Scientist; Dept. of Acoustics, Physics Faculty of MSU;
Honors/Awards: 
  • 2022 – Rayleigh-Helmholtz Interdisciplinary Silver Medal in Biomedical Acoustics and Physical Acoustics for contributions to the application of nonlinear acoustics to medical ultrasound
  • 2022 - present – Associate Editor of  the International Journal of Hyperthermia
  • 2015 - present – Elected Member of the Board of the Russian Acoustical Society (Member since 2001)
  • 2013 - 2022 – Associate Editor of  the journal IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control
  • 2012 - 2015 – Elected Member of the Executive Council of the Acoustical Society of America (ASA)
  • 2004 - 2008, 2011 - 2014 – Elected Member of the Board of the International Society for Therapeutic Ultrasound (Member since 2001)
  • 2009 - present – Member of the “Physical Ultrasound” division of the Scientific Council on Acoustics of the Russian Academy of Sciences
  • 2008 - present – Fellow of the Acoustical Society of America (Member since 1993)
  • 2008 - 2012 – Member of the Committee on Standards of ASA
  • 2008 - present – Member of the International Organizing Committee of the International Symposium on Nonlinear Acoustics 
  • 2005 - present – Member of the Committee on International Research and Education of ASA
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Publications

2017

  1. Yuldashev P. V., Tsysar S. A., Khokhlova V. A., Svet V. D., and Sapozhnikov O. A.
    "Numerical simulation of transcranial ultrasound imaging using a two-dimensional phased array"

    J. Acoust. Soc. Am.

    141
    5
    3612
  2. Wang Y.N., Khokhlova T.D., Maxwell A.D., Kreider W., Partanen A., Farr N., Schade G.R., Chernikov V.P., Buravkov S.V., Bailey M.R., Khokhlova V.A.
    "A multimodal evaluation of boiling histotripsy lesion properties in ex vivo bovine liver"

    J. Acoust. Soc. Am.

    140
    4(2)
    3082

2016

  1. T. Looi, V. Khokhlova, C. Mougenot, K. Hynynen, J. Drake
    "In vivo feasibiltiy study of boiling histotripsy with clinical sonalleve system in a neurological porcine model"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    64-66
  2. T.D. Khokhlova, G.R. Schade, Y.-N. Wang, W. Kreider, J. Simon, F. Starr, M.M. Karzova, A. Maxwell, M.R. Bailey, V.A. Khokhlova
    "Feasibility of transcutaneous volumetric boiling histotripsy ablation of liver and kidney in a pig model"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    274-276
  3. G.R. Schade, Y.-N. Wang, T.D. Khokhlova, P. May, D.W. Lin, M.R. Bailey, V.A. Khokhlova
    " Assessment of boiling histotripsy dose in human ex vivo kidneys and renal tumours"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    280-281
  4. O.A. Sapozhnikov, S.A. Tsysar, P.V. Yuldashev, V.A. Khokhlova, V.D. Svet, W. Kreider
    "Two-dimensional array synthesis using raster-scanned singlehydrophone in application to acoustic holography and ultrasound imaging"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    313-315
  5. P.V. Yuldashev, M.M. Karzova, B.W. Cunitz, B. Dunmire, W. Kreider, O.A. Sapozhnikov, M.R. Bailey, V.A. Khokhlova
    "Comparison of derating methods for nonlinear ultrasound fields of diagnostic-type transducers"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    318-321
  6. V. Khokhlova, P. Yuldashev, I. Sinilshchikov, Y. Andriyakhina, W. Kreider, A. Maxwell, T. Khokhlova, O. Sapozhnikov, A. Partanen
    "Acceleration of thermal ablation of tissue volumes in high intensity focused ultrasound therapy using shock wave exposures"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    339-342
  7. A. Rybyanets, N. Shvetsova, A. Berkovich, I. Shvetsov, O. Sapozhnikov, V. Khokhlova
    "Ultrasonic hemostatsis of deep arterial bleeding"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    343-345
  8. P.B. Rosnitskiy, S.A. Ilyin, O.A. Sapozhnikov, L.R. Gavrilov, P.V. Yuldashev, V.A. Khokhova
    "T-ARRAY: a software package for fast simulation of therapeutic ultrasound fields radiated by multi-element phased arrays"

    Program Booklet of the 16th International Symposium on Therapeutic Ultrasound (March 14 - 16, 2016, Tel Aviv, Israel)

    424-426
  9. B. Dunmire, J.C. Kucewicz, W. Kreider, T.D. Khokhlova G.R. Schade, A.D. Maxwell, O.A. Sapozhnikov, L.A. Crum, V.A. Khokhlova.
    "A training phantom for ultrasound-guided boiling histotripsy therapy."

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3308
  10. M.M. Karzova, P.B. Rosnitskiy, P.V. Yuldashev, O.A. Sapozhnikov, W. Kreider, B.W. Cunitz, M.R. Bailey, V.A. Khokhlova.
    "Modeling shock-wave fields generated by a diagnostic-type transducer"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3310
  11. T. Khokhlova, C. Hunter, W. Kreider, A. Maxwell, V. Khokhlova, and O. Sapozhnikov
    "Dependence of inertial cavitation activity on the high intensity focused ultrasound transducer F-number"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    2983
  12. T.D. Khokhlova, A.D. Maxwell., W. Kreider, V.A. Khokhlova, M. O’Donnell, and O.A. Sapozhnikov
    "A method for phase aberration correction of high intensity focused ultrasound fields using acoustic nonlinearity"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3083
  13. V.A. Khokhlova, G.R. Schade, T.D. Khokhlova, Y. Wang, J. Simon, F. Starr, A. Maxwell, M.R. Bailey, W. Kreider
    "Pilot in vivo studies on transcutaneous boiling histotripsy in porcine liver and kidney"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3030
  14. W. Kreider, C. Hunter, O.A. Sapozhnikov, A.D. Maxwell, V.A. Khokhlova, B. MacConaghy, Y.N. Wang
    "Design of transmission-mode measurements for estimating ultrasound attenuation and nonlinearity in liver"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3186
  15. A.D. Maxwell, O.A. Sapozhnikov, W. Kreider, T.D. Khokhlova, G.R. Schade, Michael R. Bailey, and Vera A. Khokhlova
    "Erosion of soft tissue by focused ultrasound-induced streaming"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3081
  16. P.B. Rosnitskiy, P.V. Yuldashev, A.D. Maxwell, W. Kreider, M.R. Bailey, O.A. Sapozhnikov, V.A. Khokhlova
    "Designing a multi-element array transducer for abdominal boiling histotripsy applications"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3082
  17. G.R. Schade, Y.-N. Wang, K. Gravelle, S. Whang, V. Pillarisetty, J. H. Hwang, W. Conrad Liles, V.A. Khokhlova, M.R. Bailey, and T.D. Khokhlova
    "Healing and the immune response following boiling histotripsy ablation of renal carcinoma in the Eker rat"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3083
  18. Y.-N. Wang, T.D. Khokhlova, A.D. Maxwell, W. Kreider, A. Partanen, N. Farr, G.R. Schade, V.P. Chernikov, S.V. Buravkov, M.R. Bailey, V.A. Khokhlova
    "A multimodal evaluation of boiling histotripsy lesion properties in ex vivo bovine liver"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3082
  19. P.V. Yuldashev, M. Hoogenboom, E. Dumont, M.H. den Brok, P.B. Rosnitskiy, O.A. Sapozhnikov, J.J. Futterer, G.J. Adema, V.A. Khokhlova
    "Characterization of high-amplitude fields of an annular array using acoustic holograms of its individual elements"

    5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, 28 November - 2 December 2016. J. Acoust. Soc. Am.

    140(4)
    2
    3082
  20. Sapozhnikov, O.A., Tsysar, S.A., Khokhlova, V.A., and Kreider, W.
    "Acoustic holography by two-dimensional ultrasound array synthesis"

    Program and Book of Abstracts of the Joint Symposium of 10th International Symposium on Medical, Bio– and Nano–Electronics, and 7th International Workshop on Nanostructures & Nanoelectonics (Tohoku University Sendai, Japan, March 1–3, 2016)

    1
  21. Khokhlova, V., Sinilshchikov, I., Yuldashev, P., Andriyakhina, Y., Kreider, W., Maxwell, A., Khokhlova, T., Sapozhnikov, O., and Partanen, A.
    "Use of shock-wave exposures for accelerating thermal ablation of confined tissue volumes"

    Program and Abstract Book of the 5th International Symposium on Focused Ultrasound (August 28 – September 1, 2016, Bethesda, MD, USA), Focused Ultrasound Foundation

    81-82
  22. Sapozhnikov, O., Rosnitskiy, P., and Khokhlova, V.
    "Evaluation of nonlinear effects in the acoustic field of a hemispherical focusing transducer for ultrasound applications in brain"

    Program and Abstract Book of the 5th International Symposium on Focused Ultrasound (August 28 – September 1, 2016, Bethesda, MD, USA), Focused Ultrasound Foundation

    203
  23. Rosnitskiy, P., Yuldashev, P., Maxwell, A., Kreider, W., Bailey, M., Sapozhnikov, O., and Khokhlova, V.
    "Designing a multi-element array transducer for abdominal boiling histotripsy applications"

    J. Acoust. Soc. Am.

    140
    4-2
    3082
  24. Sapozhnikov, O.A., Rosnitskiy, P.B., and Khokhlova, V.A.
    "Evaluation of nonlinear effects at the focus of a hemispherical acoustic source"

    J. Acoust. Soc. Am.

    140
    4-2
    3435